Cishek was traded to the St. Louis Cardinals for RHP Kyle Barraclough on July 24, 2015.
In a 3–2 loss to the Atlanta Braves on July 26, he made his Cardinals debut, pitching one shutout inning but getting tagged with an error on a pickoff attempt.
Cishek became a free agent when the Cardinals did not tender him a contract for the 2016 season.
Cishek signed a two-year, $10 million contract with the Seattle Mariners on December 14, 2015. The Mariners demoted Cishek to closer for the time being after he went 25 for 31 in save opportunities.
With a hip injury, he was placed on the disabled list on August 5.
The Mariners traded Cishek to the Tampa Bay Rays for Erasmo Ramrez on July 28, 2017.
Cishek signed a two-year, $13 million contract with the Chicago Cubs on December 16, 2017.
He was reactivated from Triple-A Iowa Cubs on August 20, 2019.
Cishek signed a one-year deal with the Chicago White Sox on January 14, 2020. Cishek pitched in 22 games for the Chicago White Sox in 2020, going 0–0 with a 5.40 ERA and 21 strikeouts in 20.0 innings pitched.
On September 24, the White Sox designated Cishek for the assignment. On September 28, the group released him.
Cishek signed a minor league contract with the Houston Astros organization on February 9, 2021, which included an invitation to Spring Training. Cishek requested and was granted his release on March 25, 2021.
How Tall Is Steve Cishek?
Steve Cishek stands at a height of 1.98 m.